Professor of School of Life Sciences University of Science & Technology of China

Tel: 86-551-63602489

Fax: 86-551-63601443
e-mail: bhu@ustc.tsg211.com
website: http://zebrafish.ustc.tsg211.com

PERSONAL  PROFILE
Bing Hu, professor. He graduated from USTC and obtained Bachelor Degree of Biophysics in 1989, Master Degree of Biophysics in 1992 and Doctoral Degree from Shanghai Institute of Physiology of ChineseAcademy of Sciences in 1999 (jointly trained by Shanghai Institute of Physiology of ChineseAcademy of Sciences and Medical Faculty of the University  of Hong Kong). In 2001 he served as a postdoctoral fellow at Department of Anatomy, Medical Faculty of the University of Hong Kong; from January 2002 to November 2004 he served as a postdoctoral fellow at University of California, Los  Angeles & Irvine). In 2007, before he joined into USTC, he served as a Research Officer at Department of Anatomy, Medical Faculty of the University of Hong Kong. Over the years he has studied neurodevelopment, neuronal and myelin injury and repair. He has published over 61 academic papers in SCI journals, 3 chapters in books with 2067 citations. He has been supported by 8 grants from NSFC and 3 grants from MOST. One of his major interests focuses on the single Mauthner motor neuronal regeneration as well as remyelination using zebrafish as a model organism.

SELECTED PUBLICATIONS

Rongchen Huang, Yang Xu, Min Chen, Leiqing Yang, Xinliang Wang, Yueru Shen, Yubin Huang and Bing Hu* (2022) Visualizing the Intracellular Trafficking in Zebrafish Mauthner Cells (chapter 18) in Book “Axonal Transport”  Methods and Protocols edited by Vagnoni, Alessio (section editor), Springer Nature publisher. ISBN 978-1-0716-1989-6

Suqi Zou^1,2*and Bing Hu^3*(2021) In vivo imaging reveals mature Oligodendrocyte division in adult Zebrafish. Cell Regeneration. 10 :16 https://doi.org/10.1186/s13619-021-00079-3

Chen M, Huang RC, Yang LQ, Ren DL*, Hu B*(2019) In vivo imaging of evoked calcium responses indicates the intrinsic axonal regenerative capacity of zebrafish.FASEB J. 33(6):7721-7733.

Hu BB, Chen M, Huang RC, Huang YB, Xu Y, Yin W, Li L and Hu B* (2018) In vivo imaging of mauthner axon regeneration, remyelination and synapses re-establishment after laser axotomy in zebrafish larvae. Exp Neurol. 300:67-73. 2018. Feb. https://doi.org/10.1016/j.expneurol.2017.10.028

Huang RC, Chen M, Yang LQ, Wagle M, Guo S and Hu B* (2017) MicroRNA-133b Negatively Regulates Zebrafish Single Mauthner-Cell Axon Regeneration through Targeting tppp3 in Vivo.  Front. Mol. Neurosci. 10:375. doi: 10.3389/fnmol.2017.00375

Chen, M., Xu, Y., Huang, R., Huang Yubin, Ge Shuchao and Hu Bing* (2017) N-Cadherin is Involved in Neuronal Activity-Dependent Regulation of Myelinating Capacity of Zebrafish Individual Oligodendrocytes In Vivo. Molecular Neurobiology, 54(9), 6917-6930. doi:10.1007/s12035-016-0233-4

Tian C, Zou S, Hu B*(2016) Extraocular Source of Oligodendrocytes Contribute to Retinal Myelination and Optokinetic Responses in Zebrafish. Invest Ophthalmol Vis Sci. 2016 Apr 1;57(4):2129-38. doi: 10.1167/iovs.15-17675. (highlight in the same issue)

Da-Long Ren, Ai-Ai Sun, Ya-Juan Li, Min Chen, Shu-Chao Ge and Bing Hu* (2015) Exogenous melatonin inhibits neutrophil migration through suppression of ERK activation. Journal of Endocrinology. 227(1) :49–60. DOI: 10.1530/JOE-15-0329. Epub 2015 Aug 24. (cover page)

Da-long Ren, Ya-juan Li, Bing-bing Hu, Han Wang* and Bing Hu* (2015)Melatonin regulates the rhythmic migration of neutrophils in live zebrafish. J Pineal Res., 2015 May;58(4):452-60. doi: 10.1111/jpi.12230. Epub 2015 Mar 26.

Sha Mi*, Bing Hu*, Kyungmin Hahm, Yi Luo, Edward Sai Kam Hui, Qiuju Yuan, Wai Man Wong, Li Wang, Huanxing Su, Tak-Ho Chu, Jiasong Guo, Wenming Zhang, Kwok-Fai So, Blake Pepinsky, Zhaohui Shao, Christilyn Graff, Ellen Garber, Vincent Jung, Ed Xuekui Wu & Wutian Wu* (2007) LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis. Nature Medicine. 13(10):1228-1233.

Bing Hu, Angeliki Maria Nikolakopoulou and Susana Cohen-Cory (2005) BDNF stabilizes synapses and maintains the structural complexity of optic axons in vivo. Development. 132:4285-4298.

Bing Hu, Henry K. Yip and Kwok-Fai So (1998) Localization of p75 neurotrophin receptor in the retina of the adult SD rat: An immunocytochemical study at light and electron microscopic levels. Glia 24:187-197.